DISEASES

Disease-gene associations mined from literature

Literature associating YWHAQ and Alzheimer's disease 10

YWHAQ [ENSP00000371267]

14-3-3 protein theta; Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. Negatively regulates the kinase activity of PDPK1; Belongs to the 14-3-3 family.

Synonyms:  YWHAQ,  E9PG15,  P27348,  E9PG15p,  hE9PG15 ...

Linkouts:  STRING  Pharos  UniProt