DISEASES

Disease-gene associations mined from literature

Literature associating RDH11 and aggressive systemic mastocytosis

RDH11 [ENSP00000370750]

Retinol dehydrogenase 11; Retinol dehydrogenase with a clear preference for NADP. Displays high activity towards 9-cis, 11-cis and all-trans-retinol, and to a lesser extent on 13-cis-retinol (PubMed:12226107, PubMed:12036956, PubMed:29410696). Exhibits a low reductive activity towards unsaturated medium-chain aldehydes such as cis -6-nonenal and no activity toward nonanal or 4-hydroxy-nonenal . Has no dehydrogenase activity towards steroid .

Synonyms:  RDH11,  RDH11p,  hRDH11,  A0A0S2Z583,  G3V234 ...

Linkouts:  STRING  Pharos  UniProt  OMIM