Literature associating ZDHHC21 and chromosome 9p deletion syndrome
ZDHHC21 [ENSP00000370303]
Palmitoyltransferase ZDHHC21; Palmitoylates sex steroid hormone receptors, including ESR1, PGR and AR, thereby regulating their targeting to the plasma membrane. This affects rapid intracellular signaling by sex hormones via ERK and AKT kinases and the generation of cAMP, but does not affect that mediated by their nuclear receptor (By similarity); Belongs to the DHHC palmitoyltransferase family.
Synonyms: ZDHHC21, ZDHHC21p, hZDHHC21, Q8IVQ6, Q8IVQ6p ...