DISEASES

Disease-gene associations mined from literature

Literature associating PIR and Chilblain lupus

PIR [ENSP00000369786]

Pirin; Transcriptional coregulator of NF-kappa-B which facilitates binding of NF-kappa-B proteins to target kappa-B genes in a redox- state-dependent manner. May be required for efficient terminal myeloid maturation of hematopoietic cells. Has quercetin 2,3-dioxygenase activity (in vitro). ECO:0000269|PubMed:20010624, ECO:0000269|PubMed:20711196,; Belongs to the pirin family.

Synonyms:  PIR,  A0A024RBX6,  O00625,  O00625p,  hO00625 ...

Linkouts:  STRING  Pharos  UniProt