DISEASES

Disease-gene associations mined from literature

Literature associating IL1RAPL1 and Partington syndrome

IL1RAPL1 [ENSP00000368278]

Interleukin-1 receptor accessory protein-like 1; May regulate secretion and presynaptic differentiation through inhibition of the activity of N-type voltage-gated calcium channel . May activate the MAP kinase JNK . Plays a role in neurite outgrowth (By similarity). During dendritic spine formation can bidirectionally induce pre- and post-synaptic differentiation of neurons by trans-synaptically binding to PTPRD (By similarity). ECO:0000250|UniProtKB:P59824, ECO:0000269|PubMed:12783849,; Belongs to the interleukin-1 receptor family.

Synonyms:  IL1RAPL1,  A0A0A0MR17,  Q9NZN1,  X5DNQ7,  Q9NZN1p ...

Linkouts:  STRING  Pharos  UniProt