DISEASES

Disease-gene associations mined from literature

Literature associating NR0B1 and congenital adrenal hyperplasia

NR0B1 [ENSP00000368253]

Nuclear receptor subfamily 0 group B member 1; Orphan nuclear receptor. Component of a cascade required for the development of the hypothalamic-pituitary-adrenal-gonadal axis. Acts as a coregulatory protein that inhibits the transcriptional activity of other nuclear receptors through heterodimeric interactions. May also have a role in the development of the embryo and in the maintenance of embryonic stem cell pluripotency (By similarity).

Synonyms:  NR0B1,  NR0B1p,  hNR0B1,  A6NNU8,  F1D8P4 ...

Linkouts:  STRING  Pharos  UniProt  OMIM