DISEASES

Disease-gene associations mined from literature

Literature associating EXT1 and ankylosing spondylitis 3

EXT1 [ENSP00000367446]

Exostosin-1; Glycosyltransferase required for the biosynthesis of heparan- sulfate. The EXT1/EXT2 complex possesses substantially higher glycosyltransferase activity than EXT1 or EXT2 alone. Appears to be a tumor suppressor. Required for the exosomal release of SDCBP, CD63 and syndecan .

Synonyms:  EXT1,  EXT1p,  hEXT1,  F8WF54,  H7C1H6 ...

Linkouts:  STRING  Pharos  UniProt  OMIM