DISEASES

Disease-gene associations mined from literature

Literature associating RTN3 and soft tissue chondroma

RTN3 [ENSP00000367050]

Reticulon-3; May be involved in membrane trafficking in the early secretory pathway. Inhibits BACE1 activity and amyloid precursor protein processing. May induce caspase-8 cascade and apoptosis. May favor BCL2 translocation to the mitochondria upon endoplasmic reticulum stress. In case of enteroviruses infection, RTN3 may be involved in the viral replication or pathogenesis. Induces the formation of endoplasmic reticulum tubules . ECO:0000269|PubMed:16054885, ECO:0000269|PubMed:17031492,

Synonyms:  RTN3,  RTN3p,  hRTN3,  A0A024R5C4,  B7Z4M1 ...

Linkouts:  STRING  Pharos  UniProt