DISEASES

Disease-gene associations mined from literature

Literature associating TBC1D4 and type 2 diabetes mellitus

TBC1D4 [ENSP00000366863]

TBC1 domain family member 4; May act as a GTPase-activating protein for RAB2A, RAB8A, RAB10 and RAB14. Isoform 2 promotes insulin-induced glucose transporter SLC2A4/GLUT4 translocation at the plasma membrane, thus increasing glucose uptake.

Synonyms:  TBC1D4,  TBC1D4p,  hTBC1D4,  A0A3B3IRT3,  O60343 ...

Linkouts:  STRING  Pharos  UniProt  OMIM