DISEASES

Disease-gene associations mined from literature

Literature associating KCTD12 and bipolar I disorder

KCTD12 [ENSP00000366694]

BTB/POZ domain-containing protein KCTD12; Auxiliary subunit of GABA-B receptors that determine the pharmacology and kinetics of the receptor response. Increases agonist potency and markedly alter the G-protein signaling of the receptors by accelerating onset and promoting desensitization (By similarity).

Synonyms:  KCTD12,  KCTD12p,  hKCTD12,  A0A140VJM4,  Q96CX2 ...

Linkouts:  STRING  Pharos  UniProt