DISEASES

Disease-gene associations mined from literature

Literature associating ANGPTL7 and Lutembacher's syndrome

ANGPTL7 [ENSP00000366015]

Angiopoietin-related protein 7; Has a role in the formation and organization of the extracellular matrix. In the eye, it functions as a mediator of dexamethasone-induced matrix deposition in the trabecular meshwork, the tissue responsible for the outflow of the ocular aqueous humor and for the maintenance of intraocular pressure . Is a negative regulator of angiogenesis in the cornea, and plays a major role in maintaining corneal avascularity and transparency .

Synonyms:  ANGPTL7,  ANGPTL7p,  hANGPTL7,  O43827,  O43827p ...

Linkouts:  STRING  Pharos  UniProt