DISEASES

Disease-gene associations mined from literature

Literature associating FOXE1 and postsurgical hypothyroidism

FOXE1 [ENSP00000364265]

Forkhead box protein E1; Transcription factor that binds consensus sites on a variety of gene promoters and activate their transcription. Involved in proper palate formation, most probably through the expression of MSX1 and TGFB3 genes which are direct targets of this transcription factor. Also implicated in thyroid gland morphogenesis. May indirectly play a role in cell growth and migration through the regulation of WNT5A expression. ECO:0000269|PubMed:20094846, ECO:0000269|PubMed:20484477, ECO:0000269|PubMed:21177256, ECO:0000269|PubMed:24219130,

Synonyms:  FOXE1,  FOXE1p,  hFOXE1,  O00358,  O00358p ...

Linkouts:  STRING  Pharos  UniProt  OMIM