DISEASES

Disease-gene associations mined from literature

Literature associating EDA and hypohidrosis

EDA [ENSP00000363680]

Ectodysplasin-A, membrane form; Cytokine which is involved in epithelial-mesenchymal signaling during morphogenesis of ectodermal organs. Functions as a ligand activating the DEATH-domain containing receptors EDAR and EDA2R . May also play a role in cell adhesion (By similarity). ECO:0000269|PubMed:11039935, ECO:0000269|PubMed:27144394, [Isoform 3]: Binds only to the receptor EDA2R. ; Belongs to the tumor necrosis factor family.

Synonyms:  EDA,  A0A0C4DGX3,  A0A0U5J797,  D6RA95,  Q92838 ...

Linkouts:  STRING  Pharos  UniProt  OMIM