DISEASES

Disease-gene associations mined from literature

Literature associating TGIF2 and holoprosencephaly 4

TGIF2 [ENSP00000362981]

Homeobox protein TGIF2; Transcriptional repressor, which probably repress transcription by binding directly the 5'-CTGTCAA-3' DNA sequence or by interacting with TGF-beta activated SMAD proteins. Probably represses transcription via the recruitment of histone deacetylase proteins.

Synonyms:  TGIF2,  TGIF2p,  hTGIF2,  H0YKN5,  Q9GZN2 ...

Linkouts:  STRING  Pharos  UniProt