DISEASES

Disease-gene associations mined from literature

Literature associating GLO1 and diabetic neuropathy

GLO1 [ENSP00000362463]

Lactoylglutathione lyase; Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione. Involved in the regulation of TNF-induced transcriptional activity of NF-kappa-B. Required for normal osteoclastogenesis.

Synonyms:  GLO1,  GLO1p,  hGLO1,  Q04760,  X5DNM4 ...

Linkouts:  STRING  Pharos  UniProt  OMIM