DISEASES

Disease-gene associations mined from literature

Literature associating TACR2 and constipation

TACR2 [ENSP00000362403]

Substance-K receptor; This is a receptor for the tachykinin neuropeptide substance K (neurokinin A). It is associated with G proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of affinity of this receptor to tachykinins is: substance K > neuromedin-K > substance P.

Synonyms:  TACR2,  TACR2p,  hTACR2,  A0A087WZ80,  A6NEW7 ...

Linkouts:  STRING  Pharos  UniProt  OMIM