DISEASES

Disease-gene associations mined from literature

Literature associating TSPAN15 and acute pulmonary heart disease

TSPAN15 [ENSP00000362387]

Tetraspanin-15; Regulates maturation and trafficking of the transmembrane metalloprotease ADAM10 . Promotes ADAM10-mediated cleavage of CDH2 (By similarity). Negatively regulates ligand-induced Notch activity probably by regulating ADAM10 activity ; Belongs to the tetraspanin (TM4SF) family.

Synonyms:  TSPAN15,  TSPAN15p,  hTSPAN15,  H7C285,  O95858 ...

Linkouts:  STRING  Pharos  UniProt  OMIM