DISEASES

Disease-gene associations mined from literature

Literature associating SRPX2 and oligohydramnios

SRPX2 [ENSP00000362095]

Sushi repeat-containing protein SRPX2; Acts as a ligand for the urokinase plasminogen activator surface receptor. Plays a role in angiogenesis by inducing endothelial cell migration and the formation of vascular network (cords). Involved in cellular migration and adhesion. Increases the phosphorylation levels of FAK. Interacts with and increases the mitogenic activity of HGF. Promotes synapse formation. May have a role in the perisylvian region, critical for language and cognitive development.

Synonyms:  SRPX2,  SRPX2p,  hSRPX2,  A0A1W2PNZ6,  A0A1W2PR88 ...

Linkouts:  STRING  Pharos  UniProt  OMIM