DISEASES

Disease-gene associations mined from literature

Literature associating RRAGC and cranioectodermal dysplasia

RRAGC [ENSP00000362092]

Ras-related GTP-binding protein C; Guanine nucleotide-binding protein forming heterodimeric Rag complexes required for the amino acid-induced relocalization of mTORC1 to the lysosomes and its subsequent activation by the GTPase RHEB. This is a crucial step in the activation of the TOR signaling cascade by amino acids.

Synonyms:  RRAGC,  Q9HB90,  Q9HB90p,  hQ9HB90,  3LLU ...

Linkouts:  STRING  Pharos  UniProt  OMIM