DISEASES

Disease-gene associations mined from literature

Literature associating ADIRF and inclusion body myopathy with early-onset Paget disease of bone with or without frontotemporal dementia 3

ADIRF [ENSP00000361083]

Adipogenesis regulatory factor; Plays a role in fat cell development; promotes adipogenic differentiation and stimulates transcription initiation of master adipogenesis factors like PPARG and CEBPA at early stages of preadipocyte differentiation. Its overexpression confers resistance to the anticancer chemotherapeutic drug cisplatin.

Synonyms:  ADIRF,  Q15847,  Q5TBU2,  Q5TBU5,  Q15847p ...

Linkouts:  STRING  Pharos  UniProt