DISEASES

Disease-gene associations mined from literature

Literature associating RAD54L and Bloom syndrome

RAD54L [ENSP00000361043]

DNA repair and recombination protein RAD54-like; Involved in DNA repair and mitotic recombination. Functions in the recombinational DNA repair (RAD52) pathway. Dissociates RAD51 from nucleoprotein filaments formed on dsDNA. Could be involved in the turnover of RAD51 protein-dsDNA filaments (By similarity). May play also an essential role in telomere length maintenance and telomere capping in mammalian cells.

Synonyms:  RAD54L,  RAD54Lp,  hRAD54L,  A0A087WTB0,  A0A087WV39 ...

Linkouts:  STRING  Pharos  UniProt  OMIM