Literature associating ORC1 and Meier-Gorlin syndrome
ORC1 [ENSP00000360623]
Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent. The DNA sequences that define origins of replication have not been identified yet. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication; Belongs to the ORC1 family.
Synonyms: ORC1, ORC1p, hORC1, Q13415, Q13415p ...