DISEASES

Disease-gene associations mined from literature

Literature associating DPYD and head and neck squamous cell carcinoma

DPYD [ENSP00000359211]

Dihydropyrimidine dehydrogenase [NADP(+)]; Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine. Also involved the degradation of the chemotherapeutic drug 5-fluorouracil; Belongs to the dihydropyrimidine dehydrogenase family.

Synonyms:  DPYD,  Q12882,  Q12882p,  hQ12882,  1.3.1.2 ...

Linkouts:  STRING  Pharos  UniProt  OMIM