DISEASES

Disease-gene associations mined from literature

Literature associating CUEDC2 and hypertrophy of breast

CUEDC2 [ENSP00000358953]

CUE domain-containing protein 2; Down-regulates ESR1 protein levels through the ubiquitination-proteasome pathway, regardless of the presence of 17 beta-estradiol. Also involved in 17 beta-estradiol-induced ESR1 degradation. Controls PGR protein levels through a similar mechanism.

Synonyms:  CUEDC2,  CUEDC2p,  hCUEDC2,  Q9H467,  Q9H467p ...

Linkouts:  STRING  Pharos  UniProt  OMIM