Literature associating PHGDH and 2-hydroxyglutaric aciduria
PHGDH [ENSP00000358417]
D-3-phosphoglycerate dehydrogenase; Catalyzes the reversible oxidation of 3-phospho-D- glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate and the reversible oxidation of (S)-malate to oxaloacetate; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
Synonyms: PHGDH, O43175, PGDH3, PHGDH-001, PHGDH-002 ...