Literature associating CASP7 and type 1 diabetes mellitus 17
CASP7 [ENSP00000358327]
Caspase-7 subunit p11; Involved in the activation cascade of caspases responsible for apoptosis execution. Cleaves and activates sterol regulatory element binding proteins (SREBPs). Proteolytically cleaves poly(ADP- ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Overexpression promotes programmed cell death.
Synonyms: CASP7, CASP7p, hCASP7, A0A0A0MRL7, P55210 ...