DISEASES

Disease-gene associations mined from literature

Literature associating H2AC18 and anal squamous cell carcinoma

H2AC18 [ENSP00000358155]

Histone H2A type 2-A; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

Synonyms:  H2AC18,  H2AC18p,  hH2AC18,  HIST2H2AA3,  Q6FI13 ...

Linkouts:  STRING  Pharos  UniProt