DISEASES

Disease-gene associations mined from literature

Literature associating MMP21 and visceral heterotaxy

MMP21 [ENSP00000357798]

Matrix metalloproteinase-21; Plays a specialized role in the generation of left-right asymmetry during embryogenesis. May act as a negative regulator of the NOTCH-signaling pathway . Cleaves alpha-1-antitrypsin ; Belongs to the peptidase M10A family.

Synonyms:  MMP21,  MMP21p,  hMMP21,  A0A494C0E5,  A0A494C1E5 ...

Linkouts:  STRING  Pharos  UniProt  OMIM