DISEASES

Disease-gene associations mined from literature

Literature associating NKX6-2 and maturity-onset diabetes of the young type 6

NKX6-2 [ENSP00000357581]

Homeobox protein Nkx-6.2; Transcription factor with repressor activity involved in the regulation of axon-glial interactions at myelin paranodes in oligodendrocytes. Binds to the consensus DNA sequence 5'-(A/T)TTAATGA- 3'. In oligodendrocytes, binds to MBP and PLP1 promoter regions.

Synonyms:  NKX6-2,  Q9C056,  Q9C056p,  hQ9C056,  84504 ...

Linkouts:  STRING  Pharos  UniProt