Literature associating GOPC and cystic fibrosis
GOPC [ENSP00000357484]
Golgi-associated PDZ and coiled-coil motif-containing protein; Plays a role in intracellular protein trafficking and degradation. May regulate CFTR chloride currents and acid-induced ASIC3 currents by modulating cell surface expression of both channels. May also regulate the intracellular trafficking of the ADR1B receptor. May play a role in autophagy. Overexpression results in CFTR intracellular retention and degradation in the lysosomes.
Synonyms: GOPC, F5H1Y4, Q9HD26, F5H1Y4p, hF5H1Y4 ...