DISEASES

Disease-gene associations mined from literature

Literature associating HEY2 and chronic apical periodontitis

HEY2 [ENSP00000357348]

Hairy/enhancer-of-split related with YRPW motif protein 2; Downstream effector of Notch signaling which may be required for cardiovascular development. Transcriptional repressor which binds preferentially to the canonical E box sequence 5'-CACGTG-3'. Represses transcription by the cardiac transcriptional activators GATA4 and GATA6; Belongs to the HEY family.

Synonyms:  HEY2,  HEY2p,  hHEY2,  Q5TF93,  Q9UBP5 ...

Linkouts:  STRING  Pharos  UniProt  OMIM