DISEASES

Disease-gene associations mined from literature

Literature associating NES and brain stem cancer

NES [ENSP00000357206]

Nestin; Required for brain and eye development. Promotes the disassembly of phosphorylated vimentin intermediate filaments (IF) during mitosis and may play a role in the trafficking and distribution of IF proteins and other cellular factors to daughter cells during progenitor cell division. Required for survival, renewal and mitogen- stimulated proliferation of neural progenitor cells (By similarity).

Synonyms:  NES,  P48681,  P48681p,  hP48681,  10763 ...

Linkouts:  STRING  Pharos  UniProt  OMIM