DISEASES

Disease-gene associations mined from literature

Literature associating DUSP12 and multinucleated neurons, anhydramnios, renal dysplasia, cerebellar hypoplasia and hydranencephaly

DUSP12 [ENSP00000356920]

Dual specificity protein phosphatase 12; Dual specificity phosphatase; can dephosphorylate both phosphotyrosine and phosphoserine or phosphothreonine residues. Can dephosphorylate glucokinase (in vitro) (By similarity). Has phosphatase activity with the synthetic substrate 6,8-difluoro-4-methylumbelliferyl phosphate and other in vitro substrates (PubMed:10446167, PubMed:24531476).

Synonyms:  DUSP12,  DUSP12p,  hDUSP12,  Q9UNI6,  V9GY92 ...

Linkouts:  STRING  Pharos  UniProt  OMIM