DISEASES

Disease-gene associations mined from literature

Literature associating IFNGR1 and leishmaniasis

IFNGR1 [ENSP00000356713]

Interferon gamma receptor 1; Associates with IFNGR2 to form a receptor for the cytokine interferon gamma (IFNG) (PubMed:7615558, PubMed:2971451, PubMed:7617032, PubMed:10986460). Ligand binding stimulates activation of the JAK/STAT signaling pathway . Plays an essential role in the IFN-gamma pathway that is required for the cellular response to infectious agents . ECO:0000269|PubMed:2971451, ECO:0000269|PubMed:7615558,

Synonyms:  IFNGR1,  IFNGR1p,  hIFNGR1,  A0A0S2Z3Y2,  A0A2R8Y4U4 ...

Linkouts:  STRING  Pharos  UniProt  OMIM