DISEASES

Disease-gene associations mined from literature

Literature associating SERPINC1 and factor VII deficiency

SERPINC1 [ENSP00000356671]

Antithrombin-III; Most important serine protease inhibitor in plasma that regulates the blood coagulation cascade. AT-III inhibits thrombin, matriptase-3/TMPRSS7, as well as factors IXa, Xa and XIa. Its inhibitory activity is greatly enhanced in the presence of heparin.

Synonyms:  SERPINC1,  A0A024R944,  P01008,  Q8TCE1,  P01008p ...

Linkouts:  STRING  Pharos  UniProt  OMIM