DISEASES

Disease-gene associations mined from literature

Literature associating ADGRG6 and peanut allergy

ADGRG6 [ENSP00000356581]

Adhesion G-protein coupled receptor G6; G-protein coupled receptor which is activated by type IV collagen, a major constituent of the basement membrane (By similarity). Couples to G(i)-proteins as well as G(s)-proteins . Essential for normal differentiation of promyelinating Schwann cells and for normal myelination of axons . Regulates neural, cardiac and ear development via G-protein- and/or N-terminus- dependent signaling (By similarity). May act as a receptor for PRNP which may promote myelin homeostasis (By similarity).

Synonyms:  ADGRG6,  ADGRG6p,  hADGRG6,  F5H054,  F5H2L1 ...

Linkouts:  STRING  Pharos  UniProt  OMIM