DISEASES

Disease-gene associations mined from literature

Literature associating RGS1 and congenital vertical talus

RGS1 [ENSP00000356429]

Regulator of G-protein signaling 1; Regulates G protein-coupled receptor signaling cascades, including signaling downstream of the N-formylpeptide chemoattractant receptors and leukotriene receptors . Inhibits B cell chemotaxis toward CXCL12 (By similarity). Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form (PubMed:10480894, PubMed:18434541).

Synonyms:  RGS1,  RGS1p,  hRGS1,  A0A024R945,  Q08116 ...

Linkouts:  STRING  Pharos  UniProt  OMIM