Literature associating TAB2 and ectodermal dysplasia
TAB2 [ENSP00000356426]
TGF-beta-activated kinase 1 and MAP3K7-binding protein 2; Adapter linking MAP3K7/TAK1 and TRAF6. Promotes MAP3K7 activation in the IL1 signaling pathway. The binding of 'Lys-63'-linked polyubiquitin chains to TAB2 promotes autophosphorylation of MAP3K7 at 'Thr-187'. Involved in heart development.
Synonyms: TAB2, TAB2p, hTAB2, A0A1B0GV57, Q9NYJ8 ...