Literature associating RO60 and keratoconjunctivitis sicca
RO60 [ENSP00000356416]
60 kDa SS-A/Ro ribonucleoprotein; RNA-binding protein that binds to misfolded non-coding RNAs, pre-5S rRNA, and several small cytoplasmic RNA molecules known as Y RNAs. May stabilize some of these RNAs and protect them from degradation . Binds to endogenous Alu retroelements which are induced by type I interferon and stimulate porinflammaotry cytokine secretion. Regulates the expression of Alu retroelements as well as inflammatory genes . ; Belongs to the Ro 60 kDa family.
Synonyms: RO60, RO60p, hRO60, A0A024R983, D6RDN1 ...