DISEASES

Disease-gene associations mined from literature

Literature associating TFB1M and drug-induced hearing loss

TFB1M [ENSP00000356134]

Dimethyladenosine transferase 1, mitochondrial; S-adenosyl-L-methionine-dependent methyltransferase which specifically dimethylates mitochondrial 12S rRNA at the conserved stem loop. Also required for basal transcription of mitochondrial DNA, probably via its interaction with POLRMT and TFAM. Stimulates transcription independently of the methyltransferase activity.

Synonyms:  TFB1M,  TFB1Mp,  hTFB1M,  E5KTM5,  Q8WVM0 ...

Linkouts:  STRING  Pharos  UniProt  OMIM