DISEASES

Disease-gene associations mined from literature

Literature associating DSTYK and myofibrillar myopathy 8

DSTYK [ENSP00000356130]

Dual serine/threonine and tyrosine protein kinase; Acts as a positive regulator of ERK phosphorylation downstream of fibroblast growth factor-receptor activation . Involved in the regulation of both caspase-dependent apoptosis and caspase-independent cell death . In the skin, it plays a predominant role in suppressing caspase-dependent apoptosis in response to UV stress in a range of dermal cell types .

Synonyms:  DSTYK,  Q6XUX3,  Q6XUX3p,  hQ6XUX3,  2.7.12.1 ...

Linkouts:  STRING  Pharos  UniProt  OMIM