Literature associating COQ8A and ataxia with oculomotor apraxia type 1
COQ8A [ENSP00000355741]
Atypical kinase COQ8A, mitochondrial; Atypical kinase involved in the biosynthesis of coenzyme Q, also named ubiquinone, an essential lipid-soluble electron transporter for aerobic cellular respiration (PubMed:25498144, PubMed:21296186, PubMed:25540914, PubMed:27499294). Its substrate specificity is unclear: does not show any protein kinase activity (PubMed:25498144, PubMed:27499294). Probably acts as a small molecule kinase, possibly a lipid kinase that phosphorylates a prenyl lipid in the ubiquinone biosynthesis pathway, as suggested by its ability to bind coenzyme Q lipid intermediates . Shows an unusual selectivity for binding ADP over ATP .
Synonyms: COQ8A, COQ8Ap, hCOQ8A, A0A024R3S3, CABC1 ...