Literature associating GPR137B and autosomal recessive distal hereditary motor neuronopathy
GPR137B [ENSP00000355551]
Integral membrane protein GPR137B; Lysosomal integral membrane protein that regulates the localization and activity of mTORC1, a signaling complex promoting cell growth in response to growth factors, energy levels, and amino acids . Interacts with Rag GTPases and increases the lysosomial localization and activity of Rag GTPases and thereby regulates mTORC1 translocation and activity in lysosome . Involved in the regulation of lysosomal morphology and autophagy .
Synonyms: GPR137B, GPR137Bp, hGPR137B, H0Y509, O60478 ...