Literature associating ARHGEF15 and childhood hypophosphatasia
ARHGEF15 [ENSP00000355026]
Rho guanine nucleotide exchange factor 15; Specific GEF for RhoA activation. Does not activate RAC1 or CDC42. Regulates vascular smooth muscle contractility. Negatively regulates excitatory synapse development by suppressing the synapse- promoting activity of EPHB2.
Synonyms: ARHGEF15, A0A0S2Z547, A0A3B3IUF8, J3KT46, J3QQS4 ...