Literature associating GAB2 and Alzheimer's disease 1
GAB2 [ENSP00000354952]
GRB2-associated-binding protein 2; Adapter protein which acts downstream of several membrane receptors including cytokine, antigen, hormone, cell matrix and growth factor receptors to regulate multiple signaling pathways. Regulates osteoclast differentiation mediating the TNFRSF11A/RANK signaling. In allergic response, it plays a role in mast cells activation and degranulation through PI-3-kinase regulation. Also involved in the regulation of cell proliferation and hematopoiesis.
Synonyms: GAB2, GAB2p, hGAB2, E9PJ26, E9PJE2 ...