Literature associating MAST2 and inflammatory bowel disease 6
MAST2 [ENSP00000354671]
Microtubule-associated serine/threonine-protein kinase 2; Appears to link the dystrophin/utrophin network with microtubule filaments via the syntrophins. Phosphorylation of DMD or UTRN may modulate their affinities for associated proteins. Functions in a multi-protein complex in spermatid maturation. Regulates lipopolysaccharide-induced IL-12 synthesis in macrophages by forming a complex with TRAF6, resulting in the inhibition of TRAF6 NF-kappa-B activation (By similarity); Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.
Synonyms: MAST2, MAST2p, hMAST2, E7ERL6, Q6P0Q8 ...