DISEASES

Disease-gene associations mined from literature

Literature associating MYH10 and MYH-9 related disease

MYH10 [ENSP00000353590]

Myosin-10; Cellular myosin that appears to play a role in cytokinesis, cell shape, and specialized functions such as secretion and capping. Involved with LARP6 in the stabilization of type I collagen mRNAs for CO1A1 and CO1A2. During cell spreading, plays an important role in cytoskeleton reorganization, focal contacts formation (in the central part but not the margins of spreading cells), and lamellipodial extension; this function is mechanically antagonized by MYH9. ; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

Synonyms:  MYH10,  MYH10p,  hMYH10,  E7ERA5,  P35580 ...

Linkouts:  STRING  Pharos  UniProt