DISEASES

Disease-gene associations mined from literature

Literature associating GTF3C2 and proprotein convertase 1/3 deficiency

GTF3C2 [ENSP00000352536]

General transcription factor 3C polypeptide 2; Required for RNA polymerase III-mediated transcription. Component of TFIIIC that initiates transcription complex assembly on tRNA and is required for transcription of 5S rRNA and other stable nuclear and cytoplasmic RNAs. May play a direct role in stabilizing interactions of TFIIIC2 with TFIIIC1.

Synonyms:  GTF3C2,  GTF3C2p,  hGTF3C2,  A0A087WZD8,  C9JNH7 ...

Linkouts:  STRING  Pharos  UniProt