Literature associating H3C12 and brain stem cancer
H3C12 [ENSP00000352252]
Histone H3.1; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Synonyms: H3C12, H3C12p, hH3C12, HIST1H3A, P68431 ...