DISEASES

Disease-gene associations mined from literature

Literature associating H2AC13 and Wilson-Turner syndrome

H2AC13 [ENSP00000351589]

Histone H2A type 1; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

Synonyms:  H2AC13,  H2AC13p,  hH2AC13,  A4FTV9,  HIST1H2AG ...

Linkouts:  STRING  Pharos  UniProt